Substance abuse and mental health are interconnected, with drug addiction causing changes in the body and brain that can lead to mental illness. Addiction affects the brain’s reward center, altering brain chemistry and encouraging further drug use. As a result, priorities shift and the individual becomes more focused on substance use. This cycle of guilt, emotional pain, and temporary relief can lead to mental health problems and other side effects. Chronic substance use is also linked to various health conditions, including decision-making disorders, heart disease, psychosis, and liver damage. It is essential to recognize and address these consequences when providing support and treatment to individuals struggling with addiction.